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This report explores the challenges facing research funding and performing organisations to design and manage balanced Research Infrastructure (RI) portfolios and design effective cross-border collaborations when setting up and running joint RIs. Discussions with a broad range of stakeholders took place at a dedicated workshop co-hosted by Science Foundation Ireland and the Health Research Board.

This report analyses the underlying preconditions and efficiency of Lead Agency Procedure (LAP), based on the evidence available from the many LAP partnerships among Science Europe’s members. It also contains policy recommendations for research organisations so that they gain a more accurate understanding of the Lead Agency principles and are made more able to judge on its scope and limitations.

In a globalised research ecosystem, collaboration is key. This collaboration also brings challenges linked to the diversity of scientific and legal environments. The aim of this practical guide is to provide better and more efficient means for research organisations to apply a set of optional models for cross-border collaboration and to help them achieve more successful and easier implementation.

The Roadmap, approved by the Science Europe General Assembly in November 2013, is Science Europe’s action plan to contribute to the elements of a successful research system. It acts as a framework for voluntary collective activity, providing a long-term strategy for the association. The ‘Priority Action Areas’ are those in which Science Europe members believe that there is a potential to achieve tangible and substantive progress, and where they can add real value by working together.